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Best Practices: Getting More from the Enlist® Weed Control System
Getting the most from the Enlist® weed control system starts long before the sprayer enters the field. Thoughtful planning, attention to conditions and precise application all play a role in protecting yield and the surrounding crops. Continue reading to find out more about application best practices that help support effective, on-target performance while preserving the long-term value of the Enlist weed control system.
Select the proper nozzle
Choosing the correct spray nozzle is essential for effective herbicide application because it influences many aspects of the spraying process. The right nozzle helps optimize product performance by balancing key factors such as application volume, nozzle flow rate, nozzle type, operating pressure, ground speed and nozzle spacing. These elements work together to control droplet size, which is critical for achieving proper coverage and minimizing drift.
Plan applications at the field level
Thoughtful field planning means understanding what is growing around you, including crops that are compatible with your plans and those that may be more sensitive. Before applying an Enlist® herbicide, take time to check wind speed and direction and identify neighboring crops and landscape features around the field.
Controlling spray drift to improve on-target application: Factors to consider when deciding when and how to apply an Enlist herbicide:
- Be mindful that wind direction and wind speed are within label parameters.
- Use only labeled nozzles and pressure ranges.
- Avoid temperature inversions.
- Confirm the method of application is consistent with the label.
The application guide for Enlist herbicides is available in the 2026 Product Use Guide.
Steer clear of temperature inversions
A temperature inversion happens when a warm air layer sits on top of cooler air near the ground, creating a “lid” that keeps the cooler air from mixing upward. In these conditions, spray droplets can get trapped in the warm air layer and remain suspended until winds pick up, which can lead to off-target movement. Applications should never be made when an inversion is suspected, because nearby sensitive crops, landscapes and lawns are more likely to be injured. Instead, postpone spraying, reassess conditions later in the day and only proceed when the environment is more suitable for application.
Protecting sensitive areas: Possible habitats for endangered species are sensitive areas requiring a downwind buffer as indicated on the labels for Enlist One and Enlist Duo herbicides. To reduce the chance that an Enlist herbicide contacts sensitive areas, keep a 30-foot downwind buffer (in the direction the wind is blowing) between the spray and any other area other than:
- Roads (paved or gravel surfaces)
- Planted agricultural fields (except for susceptible crops)
- Agricultural fields that have been prepared for planting
- Areas covered by the footprint of a building, feed crib or other human-made structure with walls and/or roof
Exercise runoff control measures
Responsible runoff management supports landowners, growers and surrounding ecosystems alike. Land managers and applicators should put practical mitigation practices in place that limit runoff from treated fields as much as reasonably possible. Numerous factors should be considered, including application scheduling, soil hydrologic grouping and corresponding mitigation measures.
Perform cleanout procedures & keep spray logs
Once an Enlist® herbicide application is finished, do not leave spray solution in the tank overnight. Make sure to completely drain any remaining mixture from the system. Before treating another crop, perform a full sprayer cleanout. A meticulous rinse of the tank, boom, screens, filters, hoses and nozzles is essential to reduce carryover risk and protect nearby sensitive crops. Other components, including pumps, should also be cleaned before changing products, and the strictest cleanout directions from any Enlist herbicide tank-mix partner should always be followed. Maintain detailed spray records including, but not limited to, information such as field location and number of acres sprayed, travel speed and carrier volume, crop sprayed and stage of growth. Additional cleanout and record keeping recommendations are available in the 2026 Product Use Guide.
The Enlist® weed control system is designed for long-term performance, but its success ultimately depends on how it is used season after season. As products, labels and on-farm challenges evolve, continuing to refine application practices helps protect both herbicide efficacy and neighboring fields. By staying current on stewardship guidelines and incorporating new insights, applicators can preserve the value of the Enlist weed control system and keep it working effectively for years to come. For more detailed information, see the 2026 Product Use Guide.
Key reminders
- Use a qualified nozzle that provides the best possible coverage while appropriately managing spray droplets.
- Use a minimum of 10 gallons of water carrier volume; 1015 gallons recommended for Enlist herbicides.
- Take advantage of the flexibility provided by qualified nozzles and pressure ranges to select one that allows you to balance crop coverage and droplet size.
- Only use nozzle and pressure combinations listed for Enlist Duo® or Enlist One® herbicides for every application of an Enlist herbicide.*
*Always read and follow the product label directions as well as state and local requirements.
™ ® Trademarks of Corteva Agriscience and its affiliated companies.
Following burndown, Enlist Duo® and Enlist One® herbicides with Colex-D® technology are the only herbicides containing 2,4-D that are authorized for preemergence and postemergence use with Enlist® crops. Consult Enlist® herbicide labels for weed species controlled. Enlist Duo and Enlist One herbicides are not registered for use or sale in all states and counties; are not registered in AK, CA, CT, HI, ID, MA, ME, MT, NH, NV, OR, RI, UT, VT, WA and WY; and have additional subcounty restrictions in AL, GA, TN and TX, while existing county restrictions still remain in FL. All users must check “Bulletins Live! Two” no earlier than six months before using Enlist One or Enlist Duo. To obtain “Bulletins,” consult epa.gov/espp/, call 1-844-447-3813, or email ESPP@epa.gov. You must use the “Bulletin” valid for the month and state and county in which Enlist One or Enlist Duo are being applied. Contact your state pesticide regulatory agency if you have questions about the registration status of Enlist® herbicides in your area. ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. IT IS A VIOLATION OF FEDERAL AND STATE LAW TO USE ANY PESTICIDE PRODUCT OTHER THAN IN ACCORDANCE WITH ITS LABELING. ONLY USE FORMULATIONS THAT ARE SPECIFICALLY LABELED FOR SUCH USE IN THE STATE OF APPLICATION. USE OF PESTICIDE PRODUCTS, INCLUDING, WITHOUT LIMITATION, 2,4-D-CONTAINING PRODUCTS NOT AUTHORIZED FOR USE WITH ENLIST CROPS, MAY RESULT IN OFF-TARGET DAMAGE TO SENSITIVE CROPS/AREAS AND/OR SUSCEPTIBLE PLANTS, IN ADDITION TO CIVIL AND/OR CRIMINAL PENALTIES. Additional product-specific stewardship requirements for Enlist crops, including the Enlist Product Use Guide, can be found at www.traitstewardship.com. © 2026 Corteva. 034058 LC (03/26)